Cardiovascular Disease and Its Risk Factors Among Employees of Sindh Government; A Cross-Sectional Survey from Karachi, Pakistan

Authors

  • Madiha Shafi Sindh Rangers Hospital, Karachi, Pakistan Author
  • Humaira Mehmood Health Services Academy, Islamabad, Pakistan Author
  • Saeed Afsar Sindh Rangers Hospital, Karachi, Pakistan Author
  • Zoaib Raza Bokhari Sindh Rangers Hospital, Karachi, Pakistan Author
  • Saleem Abbasi ARI Research Cell, Children Hospital, Pakistan Institute of Medical Sciences, Islamabad, Pakistan Author

DOI:

https://doi.org/10.37978/tijfs.v3i2.52

Keywords:

Cardiovascular Diseases, Ischemic Heart Disease, Risk Factors

Abstract

Introduction:  Globally it is documented that CVD has multi-factorial aetiology and many factors like increased BMI, hypertension (HTN), stress and diabetes determine the risk of CVD. The prevalence of risk factors for cardio vascular disease (CVD) is on increase in the developing nations of the world.

Objectives: The purpose of the study was   to find out the prevalence of cardiovascular disease and its risk factors among employees of Sindh Government in Karachi, Pakistan.
Method: It was hospital based cross sectional study. A total of 150 subjects (govt employees of Sindh Government) were interviewed by using consecutive sampling technique. Data on serum cholesterol, BMI, blood pressure, history of hypertension, diabetes and cardiovascular diseases was collected, in addition to demographic data.

Results: Out of 150 subjects interviewed, 20.6% reported to have CVD. The most prevalent risk factor was hypertension, found in 58% respondents. Other risk factors were diabetes (45%), sedentary life style (50%), obesity (28%), dyslipidaemia (30%), smoking (20%), positive family history (26%). In 6% of subjects, three major risk factors were present. The risk factors, strongly associated with CVD in our study were diabetes (p<0.01), hypertension (p<0.001) and family history of CVD (p<0.02). There is strong association of increasing age on risk of developing CVD (p< 0.001).

Conclusion: The results show that there is high frequency of CVD risk factors in employees of health department in Karachi. The high prevalence of risk factors, especially hypertension, sedentary life style, obesity and diabetes should be of great concern.

References

Tunstall-Pedoe H, ed. (for the WHO MONICA Project) MONICA Monograph and Multimedia Sourcebook.World largest study of heart disease, stroke, risk factors and population trends. 1979–2002. Geneva, World Health Organization, 2003

Paradis G, Chiolero A. The Cardiovascular and Chronic

Diseases Epidemic in Low- and Middle-Income CountriesA Global Health Challenge. J Am Coll Cardiol. 011;57(17):1775–7

Okafor C, Anyaehie U, Ofoegbu E. The magnitude of obesity and its relationship to blood pressure among the residents of Enugu metropolis in South East Nigeria. Annals of Med Health Sci Res. 2014;4(4):624

Bhurgri A, Bhurgri Y, Khan Y, Sharih U, Naqvi F, Soomro I B. Mortality statistics in South Karachi. Journal of Pakistan Medical Association (2001);51(12): 446-449.

Ahmad I, Shafique Q. Myocardial infarction under age 40: Risk factors and coronary arteriographic findings. Annals of King Edward Medical College (2003);9(4):262- 265.

Jafary M H, Samad A, Ishaq M, Jawaid S A, Ahmad M, Vohra E A. Profile of acute myocardial infarction (AMI) in Pakistan. Pakistan Journal of Medical Sciences (2007); 23(4):485-489.

Saleheen D, Frossard P. CAD risk factors and acute myocardial infarction in Pakistan. Acta Cardiologica (2004);59(4):417-424.

Anand S S, Islam S, Rosengren A, Franzosi M G, Steyn K, Yusufali A H, … Yusuf, S. Risk factors for myocardial infarction in women and men: insights from the INTERHEART study. European Heart Journal (2008);29(7): 932-940.

Grundy SM. Pre-Diabetes, Metabolic Syndrome, and Cardiovascular Risk. J Am Coll Cardiol. 2012;59(7):635– 43.

Rosengren A, Hawken S, Ounpuu S, Sliwa K, Zubaid M, Almahmeed W A, Yusuf S. Association of psychosocial risk factors wih risk of acute myocardial infarction in 11,119 cases and 13,648 controls from 52 countries (The INTERHEART Study): Case-control study. Lancet (2004);364(9437):953-62.

Ridker P M, Rifai N, Rose L, Buring J E, Cook N R. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. New England Journal of Medicine (2002);347:1557-1565.

Hardoon S L, Whincup P H, Lennon L T, Wannamethee S G, Capewell S, Morris R W. How much of the recent decline in the incidence of myocardial infarction in British men can be explained by changes in cardiovascular risk factors. Circulation (2008);117:598-604.

Ahaneku GI, Osuji CU, Anisiuba BC, Ikeh VO, Oguejiofor OC, Ahaneku JE. Evaluation of blood pressure and indices of obesity in a typical rural community in eastern Nigeria. Ann Afr Med. 2011;10(2):120–64

Yusuf S, Hawkin S, Ounpuu S, Sliwa K, Zubaid M, Blackett KN, et al . Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART Study): Case control study. Lancet. 2004;364:937-52

Nishtar S, Wierzbicki AS, Lumb PJ et al. Coronary artery disease in Pakistanis. Curr Med Res Opin. 2004;20:55-62.

Hanif A.,Akhtar B, Butt A, Butt N.S, Khan B.Z, Sajid

M.R. Statistical Approach to Predict the Ischemic Heart Disease. Special Edition Annals Vol 16(1). Jan. - Mar. 2010

AbbasS, Kitchlew AR , AbbasS. Disease Burden of Ischemic Heart Disease in Pakistan and its Risk Factors. Ann. Pak. Inst. Med. Sci. 2009; 5(3): 145-150

Amin F1, Fatima SS2, Islam N3, Gilani AH. Prevalence of obesity and overweight, its clinical markers and associated factors in a high risk South-Asian population.BMC Obes. 2015 Mar 18;2:16. doi: 10.1186/s40608-015-0044-6. eCollection 2015

Dennis B1, Aziz K, She L, Faruqui AM, Davis CE, Manolio TA, Burke GL, Aziz Su High rates of obesity and cardiovascular disease risk factors in lower middle class community in Pakistan: the Metroville Health Study. J Pak Med Assoc. 2006 Jun;56(6):267-72.

AL-Nooh AA, Alajmi AAA,Wood D.The Prevalence of Cardiovascular Disease Risk Factors among Employees in the Kingdom of Bahrain between October 2010 and March 2011: A Cross-Sectional Study from a Workplace Health Campaign. Cardiology Research and Practice Volume 2014 (2014), Article ID 832421, 9 pages http://dx.doi.org/10.1155/2014/832421

World Health Organization: Physical Status: The Use And Interpretation of Anthropometry - Report of a WHO Expert Committee. 1995, Geneva: WHO Technical Report Series, 854.

World Health Organization: Obesity: Preventing and managing the global epidemic- Report of a WHO consultation. 2000, WHO Technical Report Series, 894.)

ATP III GUIDELINES At-A-Glance Quick Desk Reference PDF, National Cholesterol Education Program, Retrieved 2013-03-09.

In Memoriam: William B. Kannel (1923-2011). Tex Heart Inst J 2011;38:615–6.8. British Nutrition)

Rasool S A, Hasan S, Ghani N, Malik Z. Pattern of conventional risk factors in Coronary Artery Disease patients.Pak J Physiol 2013;9(2)

Chobanian AV, Bakris GL, Black HR, et al. The seventh report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report. JAMA 2003;289:2560-2571

S. Safdar, A. Omair, U. Faisal, H. Hasan . Prevalence of Hypertension in a low income settlement of Karachi, Pakistan. J Pak Med assoc. 2004 Oct;54(10):506-9.

Misra A, Vikram NK. Insulin resistance syndrome (metabolic syndrome) and obesity in Asian Indians: evidence and implications. Nutrition 2004; 20(5) : 482-91.

Walia R, Bhansali A, Ravikiran M, Ravikumar, et al. High prevalence of cardiovascular risk factors in Asian Indians: A community survey - Chandigarh Urban Diabetes Study (CUDS). Indian J Med Res 139, February 2014, pp 252-9.

S. P. Iqbal, S. Dodani, R. Qureshi Risk Factors and Behaviours for Coronary Artery Disease (CAD) among Ambulatory Pakistanis. Journal of Pakistan Medical Association, May 2004, Vol. 54, No. 5: 261-66.

Esteghamati AR, Abbasi M, Nakhjavani M , et al. Prevalence of diabetes and other cardiovascular risk factors in an Iranian population with acute coronary syndrome.17

July 2006 Cardiovascular Diabetology , 5:15 doi:10.1186/1475-2840-5-15

Ravikumar P, Bhansali A, Ravikiran M, Bhansali S, Walia 28. R, Shanmugasundar G, et al. Prevalence and risk factors of diabetes in a community-based study in North India: the Chandigarh Urban Diabetes Study (CUDS). Diabetes Metab 2011; 37 : 216-21.

Khan M S, Khan A, Ali A, Akhtar N, et al. Prevalence of Risk Factors for Coronary Artery Disease in Southern Punjab, Pakistan. Tropical Journal of Pharmaceutical Research January 2016; 15 (1): 195-200

Wilhelmsen L. Synergistic effects of risk factors: clinical and experimental hypertension, part A, 1990; 12:845-863

A. A. Al Riyami and M. Afifi, “Clustering of cardiovascular risk factors among Omani adults,” Eastern Mediterranean Health Journal, vol. 9, no. 5-6, pp. 893–903, 2003

Grundy S M; Pasternak R; Greenland P, Smith S, Fuster J V, Assessment of Cardiovascular Risk by Use of Multiple- Risk-Factor Assessment Equations. Circulation. 1999;100:1481-1492 Print ISSN: 0009-7322. Online ISSN: 1524-4539

Downloads

Published

2019-07-10

How to Cite

1.
Shafi M, Mehmood H, Afsar S, Bokhari ZR, Abbasi S. Cardiovascular Disease and Its Risk Factors Among Employees of Sindh Government; A Cross-Sectional Survey from Karachi, Pakistan. Int J Front Sci [Internet]. 2019 Jul. 10 [cited 2024 Sep. 18];3(2):84-90. Available from: https://p2024.frontierscienceassociates.com.pk/index.php/tijfs/article/view/44

Share

Similar Articles

1-10 of 55

You may also start an advanced similarity search for this article.