Non-Ossifying Fibroma in Posterior Mandible, A Case Report

Non-Ossifying Fibroma in Posterior Mandible

Authors

  • Maryam Zafar Department of Oral and Maxillofacial Surgery, Abbasi Shaheed Hospital, North Nazimabad, Karachi, Pakistan Author
  • Aiman Sheikh Department of Oral and Maxillofacial Surgery, Abbasi Shaheed Hospital, North Nazimabad, Karachi, Pakistan Author
  • Sufyan Ahmad Department of Oral and Maxillofacial Surgery, Abbasi Shaheed Hospital, North Nazimabad, Karachi, Pakistan Author

DOI:

https://doi.org/10.37978/tijfs.v7i1.410

Keywords:

Neoplastic, Non-Ossifying Fibroma, MetaPhysis

Abstract

In this case report, we present a case of non-ossifying fibroma in the mandible of an eleven-year-old girl who reported to the Oral and Maxillo-Facial Surgery Department with facial asymmetry and painless swelling on palpation over the lower right mandibular region. In this paper, we review the radiographic features, clinical presentation, and histopathological features of non-ossifying fibromas. Non-ossifying fibromas present with a unique extra-gnathic appearance in the skull. It is usually asymptomatic and has diverse histological features. Co-related histological, radiological, and clinical features differentiate it from other odontogenic and non-odontogenic tumors and cysts of the oral cavity. Ortho-pantogram revealed a well-demarcated, expansile radiolucency with pronounced sclerotic borders with striations reaching the anterior and superior regions and thus slowly approaching a multilocular stage. The treatment plan comprised of excisional resection with curettage under general anesthesia. After excisional biopsy of the lesion, the specimen was sent for histopathological evaluation in neutrally buffered 10 % formalin solution, which confirmed it to be a Non-Ossifying Fibroma. Prior to surgery, informed consent and written permission to collaborate with a case report encompassing her findings were obtained from the patients’ guardians. Confidentiality of patient has been taken care of before documenting the report. A meticulous literature review of previous case reports on non-ossifying fibromas revealed typical behaviors and characteristics of this lesion.

References

Chandini R, Saranya R, Mohideen K, Balasubramaniam M, Ghosh S, Dhungel S. Juvenile psammomatoid ossifying fibroma of the maxilla and mandible: A systematic review of published case reports. Clinical and Experimental Dental Research. 2023 Feb;9(1):186. doi: 10.1002/cre2.687. Epub 2022 Nov 3. DOI: https://doi.org/10.1002/cre2.687

Betsy M, Kupersmith LM, Springfield DS. Metaphyseal fibrous defects. JAAOS-Journal of the American Academy of Orthopaedic Surgeons. 2004 Mar 1;12(2):89-95. doi: 10.5435/00124635-200403000-00004. DOI: https://doi.org/10.5435/00124635-200403000-00004

Wadhwa V, Thakkar RS, Carrino JA, Chhabra A. Enlarging nonossifying fibroma mimicking aggressive bone tumour. Indian journal of cancer. 2013 Oct 1;50(4):301. DOI: 10.4103/0019-509X.123634 DOI: https://doi.org/10.4103/0019-509X.123634

Montgomery AH. Ossifying fibromas of the jaw. Archives of Surgery. 1927 Jul 1;15(1):30doi:10.1001/archsurg.1927.0113019003300 DOI: https://doi.org/10.1001/archsurg.1927.01130190033002

B?a? M, Palczewski P, ?wi?tkowski J, Go??biowski M. Cortical fibrous defects and non-ossifying fibromas in children and young adults: The analysis of radiological features in 28 cases and a review of literature. Polish journal of radiology. 2011 Oct;76(4):32doi: 11.5465/00124635-210403000-00094.

Goldin A, Muzykewicz DA, Dwek J, Mubarak SJ. The aetiology of the non-ossifying fibroma of the distal femur and its relationship to the surrounding soft tissues. Journal of children's orthopaedics. 2017 Oct;11(5):373-9. DOI: 10.1302/1863-2548.11.170068 DOI: https://doi.org/10.1302/1863-2548.11.170068

Abdelsayed RA, Sharma S, Ferguson H. Fibrous cortical defect (nonossifying fibroma) of the mandibular ramus: report of 2 cases. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2010 Oct 1;110(4):504-8. DOI: 10.1016/j.tripleo.2010.04.047. DOI: https://doi.org/10.1016/j.tripleo.2010.04.047

Katanec T, Budak L, Brajdi? D, Gabri? D. Atypical peripheral ossifying fibroma of the mandible. Dentistry Journal. 2022 Jan 6;10(1):9. doi: 10.3390/dj10010009. DOI: https://doi.org/10.3390/dj10010009

Clark M, Brierley DJ, Chan CH, Hughes D, Shadid O. Non?ossifying fibroma of the mandible: A case report and review of the literature. Oral Surgery. 2023 Jul 31. doi: 10.3390/dj10010009. DOI: https://doi.org/10.1111/ors.12837

Ryabets-Lienhard A, Grimbly C, Ward L, Antoniak K, Abousamra O. PMON306 A Multisite Study Evaluating Frequency and Characteristics of Non-Ossifying Fibromas in Children with Congenital Forms of Rickets. Journal of the Endocrine Society. 2022 Nov 1;6(Supplement_1): A622https://doi.org/10.1210/jendso/bvac150.1290 DOI: https://doi.org/10.1210/jendso/bvac150.1290

Slootweg PJ. Comparison of giant cell granuloma of the jaw and non?ossifying fibroma. Journal of Oral Pathology & Medicine. 1989 Mar;18(3):1doi10.1111/j.16000714.1989.tb00750.x. DOI: https://doi.org/10.1111/j.1600-0714.1989.tb00750.x

Pandiar D, Anbumani P, Krishnan RP. Literature Review, Case Presentation and Management of Non-ossifying Fibroma of Right Angle of Mandible: More Than just a Cortical Defect! Indian Journal of Otolaryngology and Head & Neck Surgery. 2023 Aug 7:1-8. Doi.10.1007/s12070-023-04110-8 DOI: https://doi.org/10.1007/s12070-023-04110-8

Khandaitkar S, Lamba G, Kolte V, Shenoi R, Shukla D. Non-ossifying Fibroma of Mandible in a Four-Year-Old Girl: A Case Report. Cureus. 2023 Mar 21;15(3).DOI:10.7759/cureus.36470 Corpus ID: 257675929; DOI: https://doi.org/10.7759/cureus.36470

Cherix S, Bildé Y, Becce F, Letovanec I, Rüdiger HA. Multiple non-ossifying fibromas are a cause of pathological femoral fractures in JaffeCampanacci syndrome.BMCMusculoskeletaldisor2014;15:218.doi:10.1186/1471-2474-15-218. DOI: https://doi.org/10.1186/1471-2474-15-218

Ide F, Kusuhara S, Onuma H, Miyake T, Umemura SI. XANTHIC VARIANT OF NON?OSSIFYING FIBROMA (SO?CALLED XANTHOFIBROMA) OF THE MANDIBLE: An Ultrastructural Study. Pathology International. 1982 Jan;32(1):135-42. DOI: 10.1111/j.1440- DOI: https://doi.org/10.1111/j.1440-1827.1982.tb02034.x

Hammad Y, Schlieve T. Metachronous odontogenic keratocyst and non-ossifying fibroma of the mandible. Oral and Maxillofacial Surgery Cases. 2021 Sep 1;7(3):100221. DOI: 10.1016/J.OMSC.2021.100221 DOI: https://doi.org/10.1016/j.omsc.2021.100221

Khan SA, Sharma NK, Raj V, Sethi T. Ossifying fibroma of maxilla in a male child: Report of a case and review of the literature. National journal of maxillofacial surgery. 2011 Jan;2(1):73. doi: 10.4103/0975-5950.85859. DOI: https://doi.org/10.4103/0975-5950.85859

Tanaka T, Kobayashi T, Iino M. Transformation of benign fibrous histiocytoma into malignant fibrous histiocytoma in the mandible: case report. Journal of Oral and Maxillofacial Surgery.2011Jul1;69(7):e28510.1016/j.joms.2011.02.067 DOI: https://doi.org/10.1016/j.joms.2011.02.067

Alshehri K, Fadil AA, ALSHEHRI K. Non-ossifying Fibroma Pathological Fracture in a Patient With Lactose Intolerance. Cureus. 2021 Aug 16;13(8). doi: 10.7759/cureus.17225. eCollection 2021 Aug. DOI: https://doi.org/10.7759/cureus.17225

Rawal YB, Chandra SR, Hall JM. Central xanthoma of the jaw bones: A benign tumor. Head and NeckPathologyDOI: 10.1007/s12105-016-0764-z

Rawal YB, Chandra SR, Hall JM. Central xanthoma of the jaw bones: A benign tumor. Head and Neck Pathology

doi: 10.1007/s12105-016-0764-z. DOI: https://doi.org/10.1007/s12105-016-0764-z

Downloads

Published

2024-07-25

How to Cite

1.
Zafar M, Sheikh A, Ahmad S. Non-Ossifying Fibroma in Posterior Mandible, A Case Report: Non-Ossifying Fibroma in Posterior Mandible. Int J Front Sci [Internet]. 2024 Jul. 25 [cited 2024 Sep. 16];7(1). Available from: https://p2024.frontierscienceassociates.com.pk/index.php/tijfs/article/view/112

Share